QResear.ch

#23385777 at 2025-07-26 19:36:44 (UTC+1)
Q Research General #28498: How Do You Hide A Message In Clear Sight? DS Weak END Edition

mRNA Injections Induce Severe, Long-Lasting Genetic Disruption Linked to Cancer and Chronic Disease

In a groundbreaking landmark study titled "Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination"-just uploaded to Preprints.org-we discovered that COVID-19 mRNA injections can trigger profound, long-lasting genetic dysregulation in individuals who develop new-onset adverse events or cancer following vaccination.

The study was conducted by scientists from Neo7Bioscience (Dr. John Catanzaro, Dr. Natalia von Ranke, Dr. Wei Zhang, Dr. Philipp Anokin), the University of North Texas (Dr. Danyang Shao, Dr. Ahmad Bereimipour, Minh Vu), the McCullough Foundation (Dr. Peter McCullough and Nicolas Hulscher) and Medicinal Genomics (Kevin McKernan).

Using high-resolution RNA sequencing of blood samples and differential gene expression analysis, we found that COVID-19 "vaccines" severely disrupted the expression of thousands of genes-inducing mitochondrial failure, immune system reprogramming, and oncogenic activation that persisted for months to years after injection.

Methods
The study analyzed whole blood RNA profiles from:

3 patients with new-onset adverse events (neurological, cardiovascular, chronic fatigue) following mRNA vaccination
7 patients newly diagnosed with cancer post-mRNA vaccination
803 healthy controls
Key tools and analyses:

Bulk RNA sequencing (Illumina NextSeq) of patient blood samples
DESeq2 for differential gene expression analysis
Gene Set Enrichment Analysis (GSEA) to identify disrupted biological pathways
STRING + Cytoscape to visualize protein-protein interaction (PPI) networks of dysregulated genes
Findings
mRNA Vaccines Trigger Transcriptomic Chaos
Both vaccine injured groups showed massive gene dysregulation compared to healthy controls-hundreds of genes up- or down-regulated, especially in pathways tied to:

Mitochondrial dysfunction
Protein folding and degradation stress (proteasome pathways)
Ribosomal overload and nonsense-mediated decay (NMD)
Chronic systemic inflammation
Oncogenic activation (MYC) and tumor suppressor suppression (p53, KRAS)
Shared Hallmarks in Both Groups
Mitochondrial Dysfunction & Oxidative Stress
Complex I disruptions and ROS overproduction-core features of chronic fatigue and neurodegeneration.
Ribosomal Stress & Translational Overdrive
Synthetic mRNA with modified bases (N1-methylpseudouridine) appears to trigger ribosomal overload, translation errors, and RNA surveillance activation. These stress signatures are also consistent with host responses to foreign genetic material, and may reflect reverse transcription of mRNA via endogenous LINE-1 activity, residual plasmid DNA, or vector-derived promoter activity-raising the possibility of persistent transcription or genomic integration.
Proteasome Activation
Likely due to spike protein persistence and accumulation of misfolded proteins.
Endothelial Dysfunction & Coagulopathy
Genes regulating angiogenesis and coagulation were downregulated-mirroring thrombotic complications post-vaccination.
Oncogenic Signals
Activation of MYC, suppression of p53 and KRAS inhibitors, setting the stage for tumor growth.
Cancer Group Shows Additional Red Flags
Genomic Instability & Epigenetic Reprogramming
Strong upregulation of genes linked to chromatin remodeling, DNA methylation, and nucleosome displacement-hallmarks of early tumorigenesis.
Hyperactivation of Type I Interferon and Toll-like Receptor (TLR) Pathways
Persistent immune system stimulation via TLRs, IRFs, and JAK-STAT-common in both chronic inflammation and cancer immune escape.
ACE2 Downregulation
Both groups showed severe suppression of ACE2, activating the Ang II ? AT1R ? NF-?B/MAPK cascade-a known tumor-promoting and inflammatory loop.

https://www.globalresearch.ca/mrna-injections-severe-long-lasting-genetic-disruption-cancer-chronic-disease/5895844

#15530235 at 2022-02-02 21:51:27 (UTC+1)
Q Research General #19639: We're Not Gonna Take It Anymore Edition

>>15529814

Pharmacol Res. 2021 Jan; 163: 105207.
Published online 2020 Sep 21. doi: 10.1016/j.phrs.2020.105207

Ivermectin, a potential anticancer drug derived from an antiparasitic drug

Mingyang Tang,a,b,1 Xiaodong Hu,c,1 Yi Wang,a,d Xin Yao,a,d Wei Zhang,a,b Chenying Yu,a,b Fuying Cheng,a,b Jiangyan Li,a,d and Qiang Fanga,d,e,*

Author information Article notes Copyright and License information Disclaimer

Abstract

Ivermectin is a macrolide antiparasitic drug with a 16-membered ring that is widely used for the treatment of many parasitic diseases such as river blindness, elephantiasis and scabies. Satoshi ?mura and William C. Campbell won the 2015 Nobel Prize in Physiology or Medicine for the discovery of the excellent efficacy of ivermectin against parasitic diseases. Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways. This suggests that ivermectin may be an anticancer drug with great potential. Here, we reviewed the related mechanisms by which ivermectin inhibited the development of different cancers and promoted programmed cell death and discussed the prospects for the clinical application of ivermectin as an anticancer drug for neoplasm therapy.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505114/

#15217160 at 2021-12-19 03:47:50 (UTC+1)
Q Research General #19250: The Kitchen Is Empty Ghostrider - Carrier Break Approved Edition

>>15216932
Ivermectin, a potential anticancer drug

derived from an antiparasitic drug

Pharmacol Res
2021 Jan;163:105207. doi: 10.1016/j.phrs.2020.105207. Epub 2020 Sep 21.

Mingyang Tang 1, Xiaodong Hu 2, Yi Wang 3, Xin Yao 4, Wei Zhang 5, Chenying Yu 6, Fuying Cheng 7, Jiangyan Li 8, Qiang Fang 9
Affiliations expand
PMID: 32971268 PMCID: PMC7505114 DOI: 10.1016/j.phrs.2020.105207

Abstract

Ivermectin is a macrolide antiparasitic drug, derived from naturally occurring organic compound in soil, with a 16-membered ring that is widely used for the treatment of many parasitic diseases such as River Blindness, Elephantiasis and Scabies.

Satoshi Omura and William C. Campbell won the 2015 Nobel Prize in Physiology or Medicine for the discovery of the excellent efficacy of ivermectin against parasitic diseases.

Recently, ivermectin has been reported
to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways. This suggests that ivermectin may be an anticancer drug with great potential.

Here, we reviewed the related mechanisms by which ivermectin inhibited the development of different cancers and promoted programmed cell death and discussed the prospects for the clinical application of ivermectin as an anticancer drug for neoplasm therapy.

https://pubmed.ncbi.nlm.nih.gov/32971268/


This is why [they] HATE Ivermectin so
much. Not only is it going to eradicate
this alleged Worldwide 'pandemic', it will
also expose to the World that a naturally
derived CURE FOR CANCER exists!

#14176566 at 2021-07-22 21:59:34 (UTC+1)
Q Research General #17934: High-Blood-Pressure, They Say Popcorn Helps Edition

https://miningawareness.wordpress.com/2021/07/22/niaid-usaid-funded-wuhan-gain-of-function-full-paper-rand-paul-to-file-criminal-referral-to-doj-re-fauci/

NIAID-USAID Funded Wuhan Gain-of-Function Full Paper; Rand Paul to File Criminal Referral to DOJ Re Fauci

The paper is entitled:
"Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus, 2017, By
Ben Hu 1, Lei-Ping Zeng 1, Xing-Lou Yang 1, Xing-Yi Ge 1, Wei Zhang 1, Bei Li 1, Jia-Zheng Xie 1, Xu-Rui Shen 1, Yun-Zhi Zhang 2,3, Ning Wang 1, Dong-Sheng Luo 1, Xiao-Shuang Zheng 1, Mei-Niang Wang 1, Peter Daszak 4, Lin-Fa Wang 5, Jie Cui 1*, Zheng-Li Shi 1*
1 CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases of Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China, 2 Yunnan Institute of Endemic Diseases Control and Prevention, Dali, China, 3 Dali University, Dali, China, 4 EcoHealth Alliance, New York, New York, United States of America, 5 Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore

"Funding: This work was jointly funded by National Natural Science Foundation of China (81290341, 31621061) to ZLS, China Mega-Project for Infectious Disease (2014ZX10004001-003) to ZLS, Scientific and technological basis special project (2013FY113500) to YZZ and ZLS from the Ministry of Science and Technology of China, the Strategic Priority Research Program of the Chinese Academy of Sciences (XDPB0301) to ZLS, the National Institutes of Health (NIAID R01AI110964), the USAID Emerging Pandemic Threats (EPT) PREDICT program to PD and ZLS, CAS Pioneer Hundred Talents Program to JC, NRF-CRP grant (NRF-CRP10-2012-05) to LFW and WIV ªOne-Three-Fiveº Strategic Program (WIV-135-TP1) to JC and ZLS. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript".

#391463 at 2018-02-16 01:06:42 (UTC+1)
Q Research General #481: MK Ultra FATALITY, MAGA Wins Edition!

>>391433
JWH-018

Chinese Chemical Supplier Pleads Guilty To Conspiracy And Importation Of Synthetic Drugs, Controlled Substances
Jacksonville, Florida - United States Attorney A. Lee Bentley, III announces that Wei Zhang, a/k/a David Liteng (35, Tianjin, China) has pleaded guilty to conspiracy to import controlled substance analogues (synthetic cannabinoids), knowing that they were intended for human consumption. He also pleaded guilty to two counts of aiding and abetting the importation of controlled substances and cathinones, also known as "bath salts." Zhang faces a maximum penalty of 60 years in federal prison. A sentencing date has not yet been scheduled.

According to the plea agreement, in late 2010, an individual met with Dan and Kevin Louie, the owners and operators of Source1Herbs, in Toronto, Canada. Source1Herbs was a large wholesale business that sold synthetic cannabinoids and cathinones. This individual met with the owners and learned that their Chinese-based supplier was Wei Zhang, a/k/a "David Liteng." In October 2010, the individual made contact with Zhang and discussed ordering chemicals from him directly. In late February 2011, the individual and his business partner traveled to China and met with suppliers, including Zhang. During these meetings, the individual and Zhang discussed finding a replacement chemical for (1-napthoyl)indole (JWH-018), which was set to be temporarily listed as a Schedule I controlled substance by the DEA on March 1, 2011. As a result of the meeting, the individual obtained a more favorable pricing from Zhang for synthetic chemicals. Zhang, having a significant chemistry background, explained the best chemical alternatives for JWH-018 that would give the end user a similar high, including stimulant and hallucinogenic effects.

On March 1, 2011, Zhang and others exchanged e-mail communications (including news articles) for specific chemicals banned that day, which included JWH-018. One such e-mail from Zhang states, "Hi we know there will be ban jwh and similar product on 1th (sic) march. Pls let me know what happen tomorrow." When JWH-018 was placed on the DEA's banned list, Zhang and others began selling other chemicals, including AM-2201, JWH-081, JWH-122, JWH-203, JWH-210, and JWH-250. Zhang routinely shipped large quantities of those chemicals to customers in the United States, Russia, and Europe, distributing a portion of the synthetic cannabinoids through mailing facilities in the Middle District of Florida. From March 2011 through February 2012, Zhang shipped approximately 798 kilograms of these chemicals to the individual. In addition, he supplied Source1Herbs with large quantities of synthetic cannabinoids and cathinones.

On May 7, 2014, the United States Treasury Department - Office of Foreign Asset Control (OFAC) used the Kingpin Act to designate Source1Herbs and Dan and Kevin Louie, both Canadian nationals, on the Specially Designated National (SDN) List. The Kingpin Act permits the imposition of economic sanctions to preclude a variety of worldwide economic transactions.

In July 2013, the Zhang and the individual had several discussions about synthetic cannabinoids, the latest trends in the worldwide industry, and the controlled status of certain chemicals, including UR-144, 5F-UR-144, and RCS-4. Zhang sent the individual various samples of synthetic chemicals known as 5 Meo Dalt (a synthetic cathinone), A834, 5F-UR-144, JWH-308, and WIN48098. Zhang also discussed emerging synthetic cannabinoids PB-22 and 5F-PB-22, both of which were controlled substance analogues of JWH-018 at the time, and then later a Schedule I controlled substance. After receiving a spreadsheet of Zhang's inventory, the individual negotiated a purchase deal with Zhang for large quantities of UR-144, 5F-UR-144, and RCS-4. The negotiated price for approximately 773 kilograms of chemicals was $265,000, and Zhang agreed to provide the chemicals on consignment. Zhang agreed to ship mislabeled parcels containing 2 or 3 kilograms of those substances per parcel to various mailing facilities within the Middle District of Florida.

From February 3, 2014, through May 16, 2014, Homeland Security Investigations received 48 packages containing 144 kilograms of UR-144, 47 packages containing 106 kilograms of 5F-UR-144 (XLR-11), and 8 packages containing 16 kilograms of RCS-4. During the receipt of those packages, the individual further negotiated to pay Zhang $150,000 for the 266 kilograms of Schedule I controlled substances. In April 2014, Zhang traveled to the United States to retrieve $150,000 in cash for the substances, where he was ultimately arrested.
…
https:// www.justice.gov/usao-mdfl/pr/chinese-chemical-supplier-pleads-guilty-conspiracy-and-importation-synthetic-drugs